Open Access
Malignant mesothelioma – Report of two cases with different presentations
Author(s) -
Mahavir N Munot,
Ketaki Utpat,
Unnati Desai,
Jyotsna M Joshi
Publication year - 2019
Publication title -
the indian journal of occupational and environmental medicine/the indian journal of occupational and environmental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.375
H-Index - 26
eISSN - 1998-3670
pISSN - 0973-2284
DOI - 10.4103/ijoem.ijoem_237_18
Subject(s) - tunica vaginalis , mesothelioma , medicine , asbestos , peritoneum , pericardium , pathology , mesothelial cell , neoplasm , metastasis , peritoneal mesothelioma , radiology , surgery , cancer , materials science , metallurgy
Malignant pleural mesothelioma (MPM) is a rare and aggressive neoplasm that stems from the mesothelial cells lining the visceral cavities, namely, the pleura, peritoneum, pericardium, and tunica vaginalis of the testes. MPM is the most common variant of these and constitutes up to 80% of all malignant mesotheliomas. It is usually associated with asbestos exposure and is a locally invasive neoplasm that spreads along pleura and can involve lungs with locoregional metastasis. Diagnosis remains challenging due to the latency between asbestos exposure and clinical presentation and the variable clinicoradiological manifestations. Meticulous history taking, high index of, suspicion and multimodality approach toward diagnosis are the keys to better prognosis. We hereby present two interesting cases of MPM with different presentations.