Open AccessIntraocular amyloidosis with multifocal iris and anterior chamber translucent spherules
Author(s) -
Sima Das,
Sweety Tiple,
Julie Pegu,
Suneeta Dubey,
Umang Mathur,
Kaustabh Mulay,
Carol L. Shields
Publication year - 2019
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_812_19
Subject(s) - medicine , iris (biosensor) , amyloidosis , pathology , cornea , conjunctiva , amyloid (mycology) , congo red , ophthalmology , orbit (dynamics) , computer security , computer science , biometrics , engineering , aerospace engineering , chemistry , organic chemistry , adsorption
Ocular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenting as multiple iris and anterior chamber cysts. Histopathological examination with special stain like Congo Red and Transmission Electron Microscopy confirmed the diagnosis of amyloidosis. Systemic investigations ruled out systemic association confirming the diagnosis of primary ocular amyloidosis.