Open AccessCoexistence of herpes simplex virus infection in microsporidial stromal keratitis associated with granulomatous inflammation
Author(s) -
Ruchi Mittal,
Praveen Kumar Balne,
Srikant K Sahu,
Sujata Das,
Savitri Sharma
Publication year - 2017
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_761_15
Subject(s) - medicine , keratitis , herpes simplex virus , inflammation , granulomatous inflammation , stromal cell , virology , dermatology , immunology , pathology , virus
Microsporidial stromal keratitis poses several diagnostic challenges. Patients may present with corneal ulceration, marked stromal thinning, or even as a quite corneal scar. The presentation of microsporidial stromal keratitis commonly mimics viral keratitis. Microbiology scrapings are usually helpful; however, scraping and culture-negative cases pose a significant diagnostic dilemma. Histopathological examination is diagnostic but shows varying degree of inflammation, predominantly composed of polymorphonuclear leukocytes. Granulomatous inflammation, in microsporidial stromal keratitis, is never well described, and the authors in this article aim to describe the presence of granulomatous inflammation in microsporidial stromal keratitis, in patients with associated herpes simplex virus (HSV) keratitis.