Open AccessMicrosporidial stromal keratitis in an immunocompromised patient: Successful management with medical therapy
Author(s) -
Amanjot Kaur,
Srikant K Sahu,
Sanchita Mitra,
Sujata Das
Publication year - 2020
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_2348_20
Subject(s) - medicine , stromal cell , keratitis , refractory (planetary science) , dermatology , surgery , ophthalmology , pathology , physics , astrobiology
Microsporidial stromal keratitis is refractory to topical drugs and is classically described in immunocompetent hosts. A 55-year-old patient with renal transplant and oral immunosuppressants, presented with a 15-day history of redness, pain, and diminution of vision in the right eye. Slit-lamp examination revealed epithelial defect and mid-stromal infiltrate. On corneal scraping, microsporidial spores were observed. The patient was started on topical 0.02% polyhexamethylene biguanide (PHMB) and the infiltrate resolved after 6 weeks of initiation of topical therapy.