Open AccessIntravenous tocilizumab in idiopathic pediatric uveitis with refractory cystoid macular edema – A case report
Author(s) -
Kalpana Babu,
Bhagya Sudheer,
Anand Prahalad Rao
Publication year - 2019
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1938_18
Subject(s) - medicine , macular edema , fluorescein angiography , uveitis , ophthalmology , refractory (planetary science) , tocilizumab , edema , surgery , visual acuity , physics , disease , astrobiology
A 13-year-old boy with a 4-year history of idiopathic pediatric uveitis and recurrent uveitic macular edema had failed conventional immunomodulatory therapy and presented to us with a vision of 6/24 [right eye (OD)] and 6/9 [left eye (OS)]. Fluorescein angiography showed diffuse vascular leakage along with cystoid macular edema (CME). Intravenous tocilizumab (10 mg/kg body) was given as 14 injections over 12 months. Repeat fluorescein angiography every 3 months showed a dramatic improvement in the vascular leakage and resolution of CME. At 13 months OF follow-up, vision had improved to 6/9p (OD) and 6/6(OS) with no recurrence of inflammation or CME.