Open AccessClinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease
Author(s) -
Dipankar Das,
Anusha Boddepalli,
Jyotirmay Biswas
Publication year - 2019
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1800_18
Subject(s) - medicine , vogt–koyanagi–harada disease , histopathology , enucleation , uveitis , immunohistochemistry , pathology , disease , dermatology , eye disease , ophthalmology , surgery
Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease.