Open AccessTuberculous corneal ulcer with hypopyon: A case report
Author(s) -
Neethu Latiff,
Meena Lakshmipathy,
M K Janani,
Parthopratim Dutta Majumder
Publication year - 2020
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1368_19
Subject(s) - hypopyon , medicine , corneal ulcer , tuberculosis , mycobacterium tuberculosis , antimicrobial , dermatology , ocular tuberculosis , cornea , ophthalmology , surgery , pathology , microbiology and biotechnology , endophthalmitis , biology
This case report represents an unusual presentation of Mycobacterium tuberculosis-associated corneal ulcer with hypopyon. A 64-year-old man presented with a hypopyon corneal ulcer in the right eye. His corneal scrapings were negative, and the ulcer was not responding to empirical antimicrobial therapy. A real-time polymerase chain reaction from an aqueous aspirate of the right eye detected 422 copies of M. tuberculosis. Subsequent investigations revealed positive Mantoux and interferon-gamma release assay, supportive radiology. The patient was successfully treated with a course of antitubercular therapy and topical steroids. Hypopyon corneal ulcer, though a rare manifestation of ocular tuberculosis, should be considered in cases not responding to standard antimicrobial therapy.