Open AccessUse of white light in vivo confocal microscopy for the detection of spatial changes in the corneal nerves in cases of early-stage Acanthamoeba keratitis with radial keratoneuritis
Author(s) -
KuoChi Hung,
Chia-Ju Lu,
HsinYu Liu,
Yu-Chih Hou,
IJong Wang,
FungRong Hu,
Wei-Li Chen
Publication year - 2020
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1313_19
Subject(s) - acanthamoeba keratitis , acanthamoeba , stromal cell , confocal microscopy , medicine , cornea , pathology , confocal , ophthalmology , stage (stratigraphy) , corneal epithelium , stroma , keratitis , anatomy , biology , immunohistochemistry , optics , microbiology and biotechnology , paleontology , physics
Radial keratoneuritis (RK) is a common feature of Acanthamoeba keratitis (AK). In vivo confocal microscopy (IVCM) is noninvasive and provides real-time images for the diagnosis of corneal diseases by allowing the visualization of corneal structures and morphologies of living organisms at the cellular level. Images of AK with RK obtained using commercial white light IVCM devices have not been frequently evaluated. In the present study, a white light IVCM device was used to evaluate the corneal findings and describe spatial changes in the corneal nerves at different depths in cases of early-stage AK with RK.