Open AccessElevated advanced glycation end products are associated with subfoveal ellipsoid zone disruption in diabetic macular edema
Author(s) -
Neha Mishra,
Malvika Singh,
Rajendra K Singh,
Sandeep Saxena
Publication year - 2021
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1244_21
Subject(s) - medicine , diabetic macular edema , ophthalmology , diabetic retinopathy , external limiting membrane , glycation , visual acuity , macular edema , advanced glycation end product , edema , diabetes mellitus , surgery , retinal pigment epithelium , retinal , endocrinology
Advanced glycation end products (AGEs), due to increased production and a slow turnover rate, serve as mediators of "metabolic memory" even after the resolution of hyperglycemia. A prospective study was undertaken to evaluate the association of AGEs with subfoveal ellipsoid zone (EZ) disruption in diabetic macular edema (DME).