Open AccessA case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
Author(s) -
Parthopratim Dutta Majumder,
Ruchika Lakra,
G Yamuna,
Anindya K Majumder,
Viswanath Kaushik
Publication year - 2018
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_120_18
Subject(s) - medicine , golimumab , ciliary body , intraocular pressure , ultrasound biomicroscopy , ophthalmology , corticosteroid , edema , uveitis , topical steroid , surgery , immunology , glaucoma , adalimumab , rheumatoid arthritis
A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony.