Open AccessManagement of Candida glabrata infectious crystalline keratopathy with endophthalmitis following penetrating keratoplasty
Author(s) -
Ritu Nagpal,
Sunita Chaurasia,
Joveeta Joseph,
Mudit Tyagi,
Padmaja Kumari Rani,
Muralidhar Ramappa,
Rikin Shah
Publication year - 2018
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/ijo.ijo_1106_17
Subject(s) - medicine , endophthalmitis , vitrectomy , pars plana , candida glabrata , ophthalmology , surgery , corneal transplantation , histopathology , cornea , antifungal , visual acuity , dermatology , pathology
A 33-year-old male underwent an optical keratoplasty elsewhere in the right eye following which he developed endophthalmitis and subsequently underwent a pars plana vitrectomy and lensectomy. At presentation, he had a deep stromal crystalline infiltration along the graft-host junction. A large therapeutic keratoplasty was performed, and the excised corneal button was evaluated. Histopathology revealed gram-positive round-to-oval budding structures and microbiology identified the organism as Candida glabrata. He was treated with antifungals in the postoperative period. At 4 months after therapeutic keratoplasty, the patient developed recurrent endophthalmitis, following stoppage of antifungals. The treatment was reinstituted for another year, and the patient did well with a clear graft at 18-month-follow-up period after the recurrence episode. Management of infectious crystalline keratopathy with endophthalmitis is a challenging situation and requires long-term treatment.