Open AccessFDG PET/CT with SPM analysis in early diagnosis of clinically suspected osmotic demyelination syndrome with non-contributory MRI
Author(s) -
Nikhil Seniaray,
Ritu Verma,
Rajeev Ranjan,
Ethel Shangne Belho,
Dharmender Malik,
Vanshika Gupta,
Abhinav Jaimini,
Harsh Mahajan
Publication year - 2019
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_95_19
Subject(s) - medicine , hypermetabolism , magnetic resonance imaging , basal ganglia , positron emission tomography , pons , radiology , thalamus , nuclear medicine , pathology , central nervous system
Early diagnosis is imperative for adequate management of patients with osmotic demyelination syndrome (ODS), which is usually a result of rapid shifts of osmolality secondary to rapid correction of hyponatremia. Magnetic resonance imaging (MRI) with its special sequences is the investigation of choice for early detection of the osmotic changes in the brain. We report a case of clinically suspected ODS with noncontributory MRI and positive fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) scan with statistical parametric mapping (SPM) analysis, which localized the focal hypermetabolism in the basal ganglia, thalamus, pons, and cerebellum.