Open AccessKrukenburg tumors arising from rare primary sites: Role of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography in management and outcome
Author(s) -
Kasturi Rangan,
Manish Ora,
Amrin Israrahmed,
Sanjay Gambhir
Publication year - 2019
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_86_19
Subject(s) - medicine , positron emission tomography , positron emission tomography computed tomography , radiology , computed tomography , fluorodeoxyglucose , nuclear medicine , positron emission , adenocarcinoma , cancer
Krukenberg tumors described by Friedrich Ernst Krukenberg are still fascinating for their mysterious origin. It is known to be a rare entity and commonly originates from adenocarcinoma of stomach. We present three interestingly rare cases of this entity, revealed by 18 F-fluorodeoxyglucose-positron emission tomography/computed tomography (F-18 FDG-PET/CT) scan and discuss how F-18 FDG-PET/CT can prognosticate, alter the course of treatment in such patients. Ovarian metastatic deposits were detected in patients with renal cell, duodenal, and gall bladder carcinoma. Three visits were possible in patient with duodenal cancer (favorable response to therapy), two visits in renal cell cancer (progressive disease pattern) and only single visit for gall bladder cancer. Potentials of F-18 FDG-PET/CT scan for Krukenberg disease is still in exploratory phase, but it's applications in diagnosis, disease monitoring, therapeutic response monitoring, and prognosticating are unparalleled with other imaging modalities.