Open AccessConjugation of antibodies with radiogold nanoparticles, as an effector targeting agents in radiobioconjugate cancer therapy: Optimized labeling and biodistribution results
Author(s) -
Pankaj Garg,
D. K. Hazra
Publication year - 2017
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_80_17
Subject(s) - biodistribution , colloidal gold , medicine , antibody , conjugate , antigen , nanoparticle , chromatography , radiochemistry , in vitro , nanotechnology , chemistry , biochemistry , immunology , materials science , mathematics , mathematical analysis
Drug accessibility to the tumor cells is an important area of concern with an anticipation of increasing the efficacy of the drug to be delivered to a specific site. The biogenesis of gold nanoparticles using plant-mediated phytochemical extracts and their possible linkage to cancer antibodies with an aim at delivering the conjugate specifically to the tumor-associated antigen is the basic objective of the research.