Open AccessTechnetium-99m thyroid scintigraphy and human leukocyte antigen – B35 in sub-acute thyroiditis
Author(s) -
Shoukat H Khan,
Aditya Mahajan,
Bashir Ahmad Laway,
Roohi Rasool,
Tanveer Ahmad Rather
Publication year - 2018
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_74_18
Subject(s) - medicine , thyroid , thyroiditis , hormone , scintigraphy , subacute thyroiditis , gastroenterology , endocrinology
Sub-acute thyroiditis possibly caused by a viral infection of thyroid gland is associated with a surge in thyroxine levels of the patient. Women in the younger age group are affected more than men. Markedly decreased radioactive iodine thyroid uptakes in a setting of thyrotoxicosis associated with elevated thyroxine levels and reduced thyroid stimulating hormone levels usually clinches the diagnosis. Patients mostly require symptomatic treatment with non-steroidal anti-inflammatory drugs. Sub-acute thyroiditis is a self-limiting disorder with most of the patients making a complete recovery in a span of three to six months. Being geographically and ethnically different the present studies was undertaken with an objective of understanding the clinical, laboratory and thyroid uptake profiles in patients of SAT during its natural history and also find the extent of genetic influences through its association with HLA B35.