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To date, the use of sialic acid that are reported to be elevated during malignancy has been largely unexplored for tumor imaging. The purpose of the present study was to study the modeled stable conformers of n-acetyl neuraminic acid (Neu5Ac) and its radiolabeled conjugate (Tc-99m-Neu5Ac) through computational chemistry approach and its in-vitro bioevaluation in rat C6 cell lines.

Chemoinformatic Study and In vitro Bioevaluation of Tc-99m-Labeled N-Acetyl Neuraminic Acid in C6 Glioma Cells