Open AccessMultiple cutaneous metastases on 99mTC-HYNIC-TOC scan in a rare case of malignant laryngeal paraganglioma
Author(s) -
G. R. Maruthi Sankar,
Vishnukumar Rajaraman,
Rajesh Nachiappa Ganesh,
Dhanapathi Halanaik,
Nandini Pandit,
Madhusudhanan Ponnusamy
Publication year - 2018
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_54_18
Subject(s) - medicine , larynx , paraganglioma , neuroendocrine tumors , somatostatin receptor , nuclear medicine , lymph , pathology , radiology , somatostatin , anatomy
Laryngeal paraganglioma is a rare neuroendocrine tumor arising from neural crest cells of larynx, contributing to 0.6% of the laryngeal tumors. Patients usually present with compressive symptoms such as hoarseness of voice. These tumors express somatostatin receptors, which can be imaged with radioligands such as 99m Tc labeled hydrazinonicotinyl-Tyr3-octreotide (HYNIC-TOC). The percentage of malignant transformation in laryngeal paraganglioma is 2%, and they usually metastasize to lymph nodes, bone, and liver. Here, we report a 99m Tc HYNIC-TOC scan of a 55-year-old male patient with recurrent laryngeal paraganglioma, who presented with painful multiple metastatic cutaneous nodules.