Open Access18F-fluorodeoxyglucose positron emission tomography-computed tomography in initial diagnosis and treatment response evaluation of new onset refractory status epilepticus
Author(s) -
Nikhil Seniaray,
Ritu Verma,
Rajeev Ranjan,
Ethel Shangne Belho,
Harsh Mahajan
Publication year - 2020
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_34_20
Subject(s) - medicine , status epilepticus , refractory (planetary science) , etiology , positron emission tomography , neuroimaging , computed tomography , epilepsy , radiology , autoimmune encephalitis , encephalitis , pathology , immunology , virus , physics , psychiatry , astrobiology
New onset refractory status epilepticus (NORSE), is a rare, neurological condition characterised by prolonged periods of refractory epileptic seizure with no readily identifiable cause in otherwise healthy individuals. Anatomical imaging like MRI and serology is usually unremarkable. In patients who have underlying etiology as auto-immune encephalitis without any evidence of auto-antibodies FDG PET may help in early diagnosis and treatment response as it tends to accumulate in the neuronal tissue whenever there is increased blood flow, metabolic demand or increased electrical activity which reverts back with clinical recovery.