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Fluorine-18 fluorodeoxyglucose positron emission tomography/ computed tomography in hodgkin's lymphoma: Diagnostic challenge during COVID vaccination
Author(s) -
Sharjeel Usmani,
Fatma Al-Ramadhan,
Fareeda Al-Kandari,
Najeeb Ahmed
Publication year - 2021
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_31_21
Subject(s) - medicine , positron emission tomography , lymphoma , fluorodeoxyglucose , axilla , lymph , nuclear medicine , radiology , positron emission tomography computed tomography , pet ct , pathology , breast cancer , cancer
Benign metabolic uptake on fluorine-18 fluorodeoxyglucose positron emission tomography ( 18 F-FDG PET) is not uncommonly seen after immunization. We report a case of 30-year-old man with Hodgkin's lymphoma who underwent two cycles of chemotherapy. Interim 18 F-FDG PET/computed tomography demonstrated complete metabolic response of prior hypermetabolic bilateral supraclavicular and mediastinal lymph nodes. Although multiple new normal-sized hypermetabolic left axillary and subpectoral lymph nodes are noted, relevant history revealed COVID vaccine 7 days prior scan with mild FDG uptake at the left deltoid muscle. These new findings at the left axilla are likely related to recent vaccination. 18 F-FDG PET uptake in the lymph nodes is not so uncommon after immunization; relevant history is very important especially in the phase of massive immunization to avoid false interpretation.

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