Open AccessCoexistence of multiple metastatic lesions showing various grades of differentiation in a single patient with neuroendocrine tumor of lung as primary: A combined modality approach of 68Ga-DOTANOC positron emission tomography/computed tomography and 18F-fluorodeoxyglucose positron emission tomography/computed tomography imaging
Author(s) -
Sarthak Tripathy,
Sanjana Ballal,
Madhav P. Yadav,
Prashant Joshi,
Chandrasekhar Bal,
Nishikant Damle
Publication year - 2019
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_161_18
Subject(s) - medicine , neuroendocrine tumors , positron emission tomography , gastrointestinal tract , positron emission tomography computed tomography , lung , nuclear medicine , positron emission , fluorodeoxyglucose , radiology , pathology
Neuroendocrine tumors (NETs) of gastrointestinal (GI) tract and lungs are a rare variety of tumors but given their indolent nature are quite prevalent. These tumors are mostly malignant in nature and are often diagnosed in advanced stages. GI tracts are the most common sites of NETs followed by lungs, thymus, and other less common sites being ovaries, testis, and hepatobiliary system. Nuclear medicine imaging modalities include 68 Ga-DOTANOC positron emission tomography/computed tomography (PET/CT) which is sensitive for low-grade NETs and 18 F-fluorodeoxyglucose (FDG) PET/CT which is more valuable for high-grade NETs. However, intermediate-grade NETs are equally sensitive to both 68 Ga-DOTANOC PET/CT and 18F-FDG PET/CT.