Open AccessProstate-specific membrane antigen-expressing hepatic lesion: Metastatic or hepatocellular carcinoma
Author(s) -
Jayanta Das,
Sudeshna Ray,
Rohit Tapadia,
Divya Midha,
Indranil Mallick
Publication year - 2020
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_145_19
Subject(s) - medicine , glutamate carboxypeptidase ii , hepatocellular carcinoma , prostate cancer , metastasis , antigen , prostate , pathology , transmembrane protein , prostate carcinoma , prostate specific antigen , cancer research , lesion , cancer , immunology , receptor
Prostate-specific membrane antigen (PSMA) is a glycosylated type-II transmembrane protein highly expressed in certain tumor cells. It has emerged as a novel radiotracer for evaluation of prostate cancer. Increased PSMA expression in isolated liver lesion is a diagnostic challenge. Solitary liver metastasis from prostate cancer is rare. On the other hand, PSMA avid primary hepatocellular carcinoma (HCC) has been reported in literature. We report a case of PSMA expressing atypical HCC with normal alphafeto protein (AFP) and raised prostate specific antigen (PSA).