Open AccessIncremental utility of Tc-99m glucohepatonate single-photon emission computed tomography over 18F-flourodeoxyglucose positron emission tomography in diagnosis of brain tumor recurrence – Old is gold
Author(s) -
Sameer Peer,
Sandhya Mangalore,
Jitendra Saini,
Chandagaraj
Publication year - 2021
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/ijnm.ijnm_125_20
Subject(s) - medicine , positron emission tomography , magnetic resonance imaging , single photon emission computed tomography , radiology , emission computed tomography , nuclear medicine , brain tumor , positron emission , neuroimaging , pathology , psychiatry
Detection of recurrence of a brain tumor after treatment is one of the most important and challenging diagnostic problems in neuro-oncological practice. In spite of technical advances in imaging modalities, sometimes, certain clinical presentations and manifestations can lead to a diagnostic dilemma even with the best of the technical know-how. We present a case of recurrence of anaplastic oligoastrocytoma (World Health Organization Grade III), where the patient's initial clinical presentation and the F-18 flourodeoxyglucose positron emission tomography (PET) magnetic resonance imaging findings were suggestive of stroke-like migraine attacks after radiation therapy syndrome. Due to a seizure episode before PET image acquisition, intense gyral uptake was noted in the left parietal lobe which made it difficult to ascertain the presence of a tumor recurrence. However, Tc-99m glucohepatonate single-photon emission computed tomography done after 1 week revealed radiotracer uptake within the site corresponding to the primary tumor, and a diagnosis of recurrence was made.