Open AccessHepatitis C virus-associated membranoproliferative glomerulonephritis treated with directly acting antiviral therapy
Author(s) -
Subhashree Nayak,
Ashish Kataria,
Manoj Kumar Sharma,
Anjay Rastogi,
Ekta Gupta,
Avishek Singh,
Tiwari Sc
Publication year - 2018
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/ijn.ijn_235_17
Subject(s) - membranoproliferative glomerulonephritis , medicine , thrombotic microangiopathy , cryoglobulinemia , hepatitis c virus , immunosuppression , hepatitis c , glomerulonephritis , polyarteritis nodosa , membranous nephropathy , pathology , vasculitis , immunology , kidney , virus , disease
Hepatitis C virus (HCV) infection has been shown to affect kidneys with various histopathological pattern on the kidney biopsy. These commonly include a membranoproliferative glomerulonephritis (MPGN) pattern with mixed cryoglobulinemia (CG), thrombotic microangiopathy, membranous nephropathy, and vasculitis affecting medium and small vessels of the kidneys causing polyarteritis nodosa. It has been rarely associated with MPGN without detectable CG. We present one such patient who presented to us with HCV-associated MPGN without detectable CG, who recovered completely with directly acting antiviral therapy without any immunosuppression.