Open AccessA four year experience in narcolepsy from a sleep clinic at a tertiary care centre with a short review of contemporary Indian literature
Author(s) -
Ayush Goel,
Kewal Kanabar,
Vishwanath Upadhyay,
Surendra Kumar Sharma
Publication year - 2018
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_888_16
Subject(s) - narcolepsy , multiple sleep latency test , polysomnography , excessive daytime sleepiness , tertiary care , medicine , pediatrics , cataplexy , sleep disorder , psychiatry , modafinil , insomnia , apnea
Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG). The mean age of patients was 26.2±6.4 yr; one patient had associated cataplexy and another one had all four cardinal symptoms of narcolepsy. All these patients had a history of excessive daytime sleepiness (EDS). The mean body mass index was 24.2±4.7 kg/m [2] . The mean sleep latency during MSLT was 2.7±1.3 min, and the mean REM latency was 5.7±2.9 min. Narcolepsy, although rarely reported from India, should be suspected in young non-obese patients complaining of EDS and confirmed by performing MSLT following overnight PSG.