Open AccessContribution of acrB upregulation & OmpC/Ompk36 loss over the presence of blaNDM towards carbapenem resistance development among pathogenic Escherichia coli & Klebsiella spp.
Author(s) -
Arijit Pal,
Lena Dhara,
Anusri Tripathi
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_716_17
Subject(s) - klebsiella pneumoniae , meropenem , microbiology and biotechnology , escherichia coli , biology , efflux , carbapenem , enterobacteriaceae , porin , antibiotic resistance , carbapenem resistant enterobacteriaceae , beta lactamase , antibiotics , bacterial outer membrane , gene , genetics
The global spread of carbapenem-resistant Enterobacteriaceae (CRE) is an emerging clinical problem. Hence, in this study, the plausible role of extended-spectrum beta-lactamases (ESBLs)/carbapenemases, OmpC/Ompk36, acrB and their combinations was explored among CRE.