Open AccessMolecular characterization of colistin-resistant Klebsiella pneumoniae & its clonal relationship among Indian isolates
Author(s) -
Chaitra Shankar,
M. Venkatesan,
Ranjani Rajan,
Deepa Mani,
Binesh Lal,
John Antony Jude Prakash,
Shalini Anandan,
Agila Kumari Pragasam,
Kāmini Walia,
V C Ohri,
Balaji Veeraraghavan
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_2087_17
Subject(s) - colistin , klebsiella pneumoniae , multilocus sequence typing , biology , microbiology and biotechnology , gene , multiplex polymerase chain reaction , minimum inhibitory concentration , plasmid , mutation , carbapenem , genetics , polymerase chain reaction , antibiotics , genotype , escherichia coli
Klebsiella pneumoniae (KP), a common cause of invasive infections, is often extensively drug resistant in India. At present, studies on resistance mechanism and clonal relationship of KP from India are limited. The present study was undertaken to determine the resistance mechanism and clonal relationship of colistin-resistant isolates obtained from various specimens. Carbapenemases were also determined since the isolates were carbapenem resistant.