Open AccessPresence of extracellular DNA & protein in biofilm formation by gentamicin-resistant Lactobacillus plantarum
Author(s) -
Jaimee George,
Prakash M. Halami
Publication year - 2019
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_2022_17
Subject(s) - biofilm , lactobacillus plantarum , microbiology and biotechnology , bacteria , biology , multidrug tolerance , gentamicin , probiotic , antibiotics , pseudomonas aeruginosa , lactobacillus , antibiotic resistance , extracellular polymeric substance , proteinase k , lactic acid , dna , biochemistry , genetics
Bacterial biofilms a multi-layered defence, comprise extracellular DNA (eDNA) and proteins, protect bacteria from harmful environment and nutrient limitation and utilize the mutual benefits within a community. Bacterial biofilms also defend bacteria from harsh environments such as antibiotic treatment. This leads to poor antibiotic penetration, slow growth, adaptive stress responses, and formation of persister cells. This study was done to determine the relation of antibiotic resistance deciphered by the biofilms in Lactobacillus plantarum, a lactic acid bacteria (LAB) with probiotic significance.