Open AccessAssociation of −330 interleukin-2 gene polymorphism with oral cancer
Author(s) -
Prithvi Singh,
Vijay Kumar,
Mohammad Kaleem Ahmad,
Rajni Gupta,
Abbas Ali Mahdi,
Amita Jain,
Jaishri Bogra,
Girish Chandra
Publication year - 2017
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1949_15
Subject(s) - genotype , odds ratio , single nucleotide polymorphism , allele , medicine , cancer , allele frequency , gastroenterology , immunology , oncology , biology , genetics , gene
Cytokines play an important role in the development of cancer. Several single-nucleotide polymorphisms (SNPs) of cytokine genes have been reported to be associated with the development and severity of inflammatory diseases and cancer predisposition. This study was undertaken to evaluate a possible association of interleukin 2 (IL-2) (- 330A>C) gene polymorphisms with the susceptibility to oral cancer.