Open AccessTumour protein 53 is linked with type 2 diabetes mellitus
Author(s) -
Agnieszka Śliwińska,
Jacek Kasznicki,
Marcin Kosmalski,
Melania Mikołajczyk,
Aneta Rogalska,
Karolina Przybyłowska,
Ireneusz Majsterek,
Józef Drzewoski
Publication year - 2017
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1401_15
Subject(s) - medicine , diabetes mellitus , logistic regression , type 2 diabetes mellitus , body mass index , endocrinology , metabolic syndrome , metabolic control analysis , waist , triglyceride , type 2 diabetes , gastroenterology , cholesterol
Tumour protein p53 (TP53) is a stress sensitive transcription factor responsible for the control of cell survival and death to prevent from tumour formation. In vitro and animal studies have indicated that TP53 also responds to metabolic changes and influences metabolic pathways. This study was undertaken to determine the serum level of TP53 and its correlations with clinical and biochemical parameters in type 2 diabetes mellitus (T2DM) patients in comparison to non-diabetic control individuals.