Open AccessUtility of cystatin C as a potential bladder tumour biomarker confirmed by surface plasmon resonance technique
Author(s) -
Anna Tokarzewicz,
Tomasz Guszcz,
Anna Onopiuk,
Robert Kozłowski,
Ewa Gorodkiewicz
Publication year - 2018
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_124_16
Subject(s) - cystatin c , receiver operating characteristic , urology , bladder cancer , medicine , urine , urinary system , biomarker , cystatin , area under the curve , renal function , gastroenterology , cancer , chemistry , biochemistry
The determination of cystatin C (cysC) may be helpful in diagnosis and monitoring of cancer because the pathogenesis of cancer is linked with an increased activity of cysteine peptidases (cathepsins) and a decrease of cysC concentration. This study was aimed to examine the utility of cysC as a marker of bladder cancer (BCa) to be used in the diagnosis.