Open Accessp40 & thyroid transcription factor-1 immunohistochemistry: A useful panel to characterize non-small cell lung carcinoma-not otherwise specified (NSCLC-NOS) category
Author(s) -
Ritika Walia,
Deepali Jain,
Karan Madan,
Mehar Chand Sharma,
Sandeep Mathur,
Anant Mohan,
Venkateswaran K. Iyer,
Lalit Kumar
Publication year - 2017
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1221_15
Subject(s) - immunohistochemistry , adenosquamous carcinoma , subtyping , medicine , adenocarcinoma , lung cancer , pathology , carcinoma , thyroid transcription factor 1 , lung , biopsy , not otherwise specified , oncology , cancer , computer science , programming language
Accurate histopathological subtyping of non-small cell lung carcinoma (NSCLC) is essential for targeted therapeutic agents. Immunohistochemistry (IHC) is helpful in identification of different tumour subtypes. In this study two marker approaches, one each for glandular and squamous cell differentiation was applied to maximize the proportion of accurately subtyped NSCLC not otherwise specified (NOS) tumours on small biopsy samples.