Open AccessRed cell antigen phenotypes in blood donors & thalassaemia patients for creation of red cell antigen-matched inventory
Author(s) -
Shrikant Kulkarni,
Bhavika Choudhary,
Harita Gogri,
Jayashree Sharma,
Manisha Madkaikar
Publication year - 2020
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1199_18
Subject(s) - antigen , red blood cell , immunology , blood transfusion , medicine , thalassemia , rh blood group system , red cell , isoantibodies , antibody
Patients with thalasssaemia are at a risk of alloimmunization and the presence of RBC alloantibodies further complicates transfusion therapy. Matching for the critical antigens of Rh, Kell, Kidd and Duffy blood group systems has been shown to minimize alloimmunization. The aim of the present study was to create a database of extensively typed donors for clinically significant and common blood group antigens of Rh, Kidd, Kell and Duffy systems for transfusion therapy of multitransfused thalassaemic patients.