Open AccessExperimental Zika virus infection in Aedes aegypti: Susceptibility, transmission & co-infection with dengue & chikungunya viruses
Author(s) -
Devendra T. Mourya,
M D Gokhale,
Triparna Majumdar,
Pragya D. Yadav,
Vinod Kumar,
M. S. Mavale
Publication year - 2018
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/ijmr.ijmr_1142_17
Subject(s) - virology , chikungunya , zika virus , aedes aegypti , biology , dengue fever , dengue virus , virus , aedes , outbreak , vector (molecular biology) , arbovirus , serotype , aedes albopictus , transmission (telecommunications) , viral replication , larva , biochemistry , botany , engineering , gene , electrical engineering , recombinant dna
There are reports about the susceptibility of Aedes mosquitoes to ZIKV from various countries, however, no such information is available from Indian sub-continent, although, high level of group cross-reactivity of ZIKV with other flaviviruses has been reported. During outbreak situations, many cases of Dengue (DEN) and Chikungunya (CHIK) are reported. In such scenario, vector mosquitoes are likely to get co-infection/secondary-infection with one or other virus. The present study was carried out to determine the susceptibility of Indian strain of Aedes aegypti to Zika virus (ZIKV) strain (MR-766) and the effect of co-infection/super-infection with either dengue virus (serotype-2) (DENV) or chikungunya virus (CHIKV) on ZIKV replication.