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Hodgkin Lymphoma Presenting as Immune Thrombocytopenia
Author(s) -
Mili Jain,
Neetu Pandey,
Nishant Verma,
Ashutosh Kumar
Publication year - 2019
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_238_17
Subject(s) - medicine , dacarbazine , vinblastine , bleomycin , abvd , lymphoma , stage (stratigraphy) , hodgkin lymphoma , immune thrombocytopenia , disease , radiation therapy , lymphoproliferative disorders , nodular sclerosis , presentation (obstetrics) , chemotherapy , surgery , cyclophosphamide , vincristine , platelet , paleontology , biology
Immune thrombocytopenia (ITP) in lymphoid malignancies has been observed primarily in relation to chronic lymphoproliferative disorders. ITP in Hodgkin lymphoma (HL) is a rare presentation, most often reported at follow-up. We report a case of a 12-year-old female presenting with symptomatic thrombocytopenia at the time of diagnosis of HL. The patient had stage III B bulky disease with HL mixed cellularity subtype on histology. The patient was treated with adriamycin, bleomycin, vinblastine, and dacarbazine regime along with local radiation therapy and is in complete remission at 18 months of follow-up. The treatment of underlying lymphoma in such cases resolves thrombocytopenia.

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