Open AccessPrimary Neuroendocrine Carcinoma of Kidney: Report of a Rare Case
Author(s) -
Sandeep Bhaskar,
Kartick Rastogi,
Shivani Gupta,
Ankur Jindal
Publication year - 2020
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_114_18
Subject(s) - medicine , chromogranin a , nephrectomy , neuroendocrine carcinoma , etoposide , pathological , kidney , cisplatin , pathology , abdomen , immunohistochemistry , chemotherapy , general surgery , urology , radiology
Primary neuroendocrine tumor (NET) of kidney is extremely rare, with <100 cases reported so far. The aim of the present case study is to discuss the clinical and pathological findings of renal NET and review of the available literature. We herein report the case of a 42-year-old female patient, who presented with pain abdomen and hematuria. Immunohistochemistry of her nephrectomy specimen was positive for chromogranin A and CD56 and negative for uroplakin II, P40, and CD10. KI index was 60%. Due to rarity of the tumor, there are no established guidelines available for its treatment. She was treated with combination chemotherapy of cisplatin and etoposide.