Open AccessPhysiogenomics in etiopathogenesis of cholangiocarcinoma
Author(s) -
Beuy Joob,
Viroj Wiwanitkit
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_111_17
Subject(s) - malignancy , medicine , cancer , genomics , pathogenesis , pathophysiology , intrahepatic cholangiocarcinoma , bioinformatics , pathology , gene , biology , genome , genetics
Cholangiocarcinoma is a serious malignancy that is very common in the tropical countries. It is a kind of deadly primary hepatobiliary tumor. There is a wide spectrum of tumors with varying differentiation and malignancy grades. Although it has been known for a long time inmmedicine, there is no clear cut that this deadly cancer is genetic disorder or not. A systemic approach on the pathophysiology and genomics can provide useful information and help better understand the pathogenesis of cholangiocarcinoma.