Open AccessAssessment of angiogenesis in children with acute lymphoblastic leukemia based on serum vascular endothelial growth factor assay
Author(s) -
Agnieszka MiziaMalarz,
Grażyna SobolMilejska
Publication year - 2017
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/ijmpo.ijmpo_109_17
Subject(s) - medicine , lymphoblastic leukemia , angiogenesis , vascular endothelial growth factor , cancer research , vegf receptors , leukemia
Vascular endothelial growth factor A (VEGFA) is a key proangiogenic cytokine. The role of angiogenesis in acute lymphoblastic leukemia (ALL) is still unclear. The purpose of the study was to assess angiogenesis in children with ALL based on serum VEGFA level determined at diagnosis and at remission with further participant subdivision into different risk groups.