
Serum lipid and leptin concentrations in patients with Sheehan syndrome
Author(s) -
Shabir Ahmad Mir,
Tariq Shah,
Hardeep Singh,
Iram Shabir,
Bashir Ahmad Laway
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_23_18
Subject(s) - leptin , medicine , hypopituitarism , endocrinology , triglyceride , body mass index , lipid profile , hormone replacement therapy (female to male) , cholesterol , obesity , testosterone (patch)
Sheehan syndrome (SS) refers to the occurrence of hypopituitarism after parturition. Hypopituitary adults with growth hormone (GH) deficiency have abnormal body composition with increased fat mass. As leptin is secreted almost exclusively by fat cells and the circulating leptin level is proportional to total fat mass, it is expected that abnormal elevations of leptin concentrations are found in GH deficient hypopituitary patients. The present study was undertaken to evaluate the anthropometric, lipid and leptin levels in patients with SS.