Open AccessThe role of circulating microRNA in the regulation of beta cell function and insulin resistance among Indians with type 2 diabetes
Author(s) -
S Sucharita,
V Ashwini,
Jyothi S Prabhu,
ST Avadhany,
Vageesh Ayyar,
Ganapathi Bantwal
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_162_18
Subject(s) - insulin resistance , medicine , type 2 diabetes , beta (programming language) , microrna , beta cell , function (biology) , insulin , diabetes mellitus , bioinformatics , endocrinology , microbiology and biotechnology , gene , genetics , biology , computer science , programming language , islet
Circulating microRNA (miRNA/miR) levels are emerging out as markers of tissue level changes; however, their role in type 2 diabetes (T2D) needs to be explored. The study aimed to compare the circulating levels of the miRNA (miR9, miR30d, miR1, miR133a, miR29a, miR143) between T2D and gender matched controls and also to evaluate the strength of association between circulating miRNAs and beta cell function/insulin resistance among Indians with T2D.