Open AccessUltrasound liver elastography for the detection of liver fibrosis in patients with psoriasis and reactive arthritis on long-term methotrexate therapy: A cross-sectional study
Author(s) -
Sujay Khandpur,
Deepika Yadav,
Banwari Lal Jangid,
Alok Kumar,
S. Shalimar,
Devasenathipathy Kandasamy,
Raju Sharma,
Siddharth Gupta,
Ranjit Kumar,
Mani Kalaivani
Publication year - 2020
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/ijdvl.ijdvl_425_19
Subject(s) - medicine , transient elastography , liver biopsy , methotrexate , gastroenterology , psoriasis , fibrosis , cirrhosis , steatosis , elastography , aspartate transaminase , ultrasound , biopsy , radiology , alkaline phosphatase , immunology , biochemistry , chemistry , enzyme
Long-term low-dose methotrexate therapy is associated with liver fibrosis. Although liver biopsy is the gold standard for detecting fibrosis, it is an invasive procedure associated with morbidity and mortality risks. Hence noninvasive imaging techniques such as transient elastography (TE) and shear wave elastography (SWE) have been studied to measure liver stiffness.