Open AccessThe analysis of matrix metalloproteinase-8 in gingival crevicular fluid and periodontal diseases
Author(s) -
Nila Kasuma,
Fadil Oenzil,
Eryati Darwin,
Yanwirasti Sofyan
Publication year - 2018
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_97_15
Subject(s) - medicine , gingivitis , periodontitis , chronic periodontitis , dentistry , post hoc analysis , analysis of variance , periodontal disease , disease , gastroenterology
Periodontal disease, also generally called periodontitis or gum disease, is a chronic infection-induced inflammatory disease that causes tooth loss if not properly treated, and is considered as a modifying factor in systemic health. Gingival crevicular fluid (GCF) matrix metalloproteinase-8 (MMP-8) is an inflammatory marker found in periodontal pathologic conditions. Gingivitis, a nondestructive type of periodontal disease, can progress to periodontitis if left untreated. Therefore, assessing the level of MMP-8 with comfortable methods and no tissue intervention can determine the progression of the periodontal disease for a better treatment.