Evaluation of mucoadhesive dexamethasone sodium phosphate gel in the treatment of arecoline-induced oral submucous fibrosis in wister albino rats: A cross-sectional study | Zendy

VijaybhaskarC Desai | Zendy; SidramappaB Shirsand | Zendy; Arati Malpani | Zendy; Suresh Hiremath | Zendy

Open Access

Evaluation of mucoadhesive dexamethasone sodium phosphate gel in the treatment of arecoline-induced oral submucous fibrosis in wister albino rats: A cross-sectional study

Author(s) -

VijaybhaskarC Desai,

SidramappaB Shirsand,

Arati Malpani,

Suresh Hiremath

Publication year - 2020

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/ijdr.ijdr_685_19

Subject(s) - oral submucous fibrosis , medicine , dexamethasone sodium phosphate , arecoline , dentistry , pharmacology , dexamethasone , receptor , muscarinic acetylcholine receptor

The present work aimed to prepare an oral mucoadhesive gel of dexamethasone sodium phosphate to serve the purpose of treating oral submucous fibrosis by incorporating the drug in a polymeric matrix to facilitate the localisation of the drug at the absorption site, to prolong drug delivery and to provide patient convenience.

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