Open AccessA comparative study to evaluate the efficacy of lycopene and curcumin in oral submucous fibrosis patients: A randomized clinical trial
Author(s) -
G Saran,
Deepak Umapathy,
Neeta Misra,
Shivakumar Ganiga Channaiah,
Priya Singh,
Saurabh Srivastava,
Sahana Shivakumar
Publication year - 2018
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_551_16
Subject(s) - oral submucous fibrosis , medicine , curcumin , lycopene , group b , statistical significance , population , clinical trial , burning sensation , adverse effect , randomized controlled trial , dermatology , antioxidant , pharmacology , environmental health , biochemistry , chemistry
: Oral submucous fibrosis (OSMF) is a most prevalent potentially malignant disorder associated with betel quid chewing frequently observed in the Indian population. The present study conducted is much of a keen interest because there is much new information, both in the press and the medical literature, about the benefits of fresh fruits and vegetables and antioxidants (such as lycopene and curcumin) for both prevention and treatment of diseases. As clinicians, we often prescribe medications with significant adverse effects, and certainly, if armed with evidence to support using such antioxidants as safer therapeutic alternatives for treatment of OSMF.