Open AccessEffect of nonsurgical periodontal therapy on interleukin-34 levels in periodontal health and disease
Author(s) -
C. N. Guruprasad,
A.R. Pradeep
Publication year - 2018
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_527_17
Subject(s) - medicine , periodontium , chronic periodontitis , periodontitis , scaling and root planing , dentistry , gastroenterology , clinical attachment loss , interleukin , periodontal disease , cytokine
Interleukin-34 (IL-34) is a recently identified alternative ligand for colony-stimulating factor-1 receptor plays an important role in osteoclastogenesis. The aim of this study was to evaluate the IL-34 levels in gingival crevicular fluid (GCF) and plasma in subjects with chronic periodontitis and to evaluate the effect of nonsurgical periodontal therapy on the GCF and plasma IL-34 levels.