Open AccessIsolation and genetic characterization of mutans streptococci associated with dental caries in rural field practice of a dental institution: In vivo study
Author(s) -
Bipin Kumar,
H Indiresha Narayana,
B V Sreenivasa Murthy,
Sylvia Mathew,
P Damodhar,
Santhosh Kumar
Publication year - 2019
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_269_17
Subject(s) - streptococcus mutans , dental plaque , genomic dna , agarose gel electrophoresis , polymerase chain reaction , microbiology and biotechnology , restriction enzyme , genotype , population , biology , dna extraction , dentistry , dna , bacteria , genetics , medicine , gene , environmental health
Streptococcus mutans is well-known causative microorganism in the development of dental caries because they drop the plaque pH and produce acids from carbohydrates and survive in the acidic environment. It is now evident that knowledge of the bacteria enforces empirical approach to therapy, then specific antimicrobial therapy that might allow more conservative treatment options. Over the past few decades, there has been a remarkable increase in the prevalence rate of dental caries among children and the elders. Genotypic methods help in the detection and manipulation of nucleic acids which allows microbial genes to be examined directly.