Open AccessEvaluation of cytogenic damage in the form of micronuclei in oral exfoliated buccal cells in tobacco users
Author(s) -
Krishna Gopal,
M. Padma
Publication year - 2018
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_218_17
Subject(s) - buccal administration , micronucleus test , buccal swab , micronucleus , genotoxicity , chewing tobacco , buccal mucosa , analysis of variance , oral mucosa , medicine , smokeless tobacco , dentistry , biology , physiology , andrology , pathology , cancer , genetics , tobacco use , population , toxicity , oral cavity , environmental health
Variety of substances such as tobacco, UV radiation, infrared rays, X-radiations, and chemicals on oral induction results in chromosomal aberrations and production of micronucleus (MN). Among them, tobacco-specific nitrosamines are potent mutagenic agents causing oral cancer.