Open AccessCalcium sulfate-based bioactive cement for periodontal regeneration: An In Vitro study
Author(s) -
Eva C. Das,
T. V. Kumary,
P.R. Anil Kumar,
Manoj Komath
Publication year - 2019
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/ijdr.ijdr_12_18
Subject(s) - periodontal fiber , von kossa stain , alizarin red , dentistry , viability assay , chemistry , calcium hydroxide , staining , cement , materials science , in vitro , alkaline phosphatase , medicine , pathology , biochemistry , composite material , enzyme
Various types of osteoconductive graft materials are used for the management of alveolar bone defects arising out of periodontal disease. Inorganic, self-setting, bioactive bone cements are suggested to be most appropriate because they can conformally fill the bone defect and resorb progressively along with the regeneration of the host site. A new calcium sulfate-based bioactive bone cement (BioCaS) is developed, having simplicity and effectiveness for bone grafting applications. The response of primary human periodontal ligament (hPDL) cells to this material is investigated through in vitro cell culture model so as to qualify it for the repair of periodontal infrabony defects.