Calcium sulfate-based bioactive cement for periodontal regeneration: An In Vitro study | Zendy

Manoj Komath | Zendy; E Anamika Das | Zendy; T. V. Kumary | Zendy; Prabha D. Nair | Zendy

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Calcium sulfate-based bioactive cement for periodontal regeneration: An In Vitro study

Author(s) -

Manoj Komath,

E Anamika Das,

T. V. Kumary,

Prabha D. Nair

Publication year - 2019

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/ijdr.ijdr_12_18

Subject(s) - periodontal fiber , von kossa stain , alizarin red , dentistry , viability assay , chemistry , calcium hydroxide , staining , cement , dental alveolus , materials science , in vitro , alkaline phosphatase , medicine , pathology , biochemistry , metallurgy , enzyme

Various types of osteoconductive graft materials are used for the management of alveolar bone defects arising out of periodontal disease. Inorganic, self-setting, bioactive bone cements are suggested to be most appropriate because they can conformally fill the bone defect and resorb progressively along with the regeneration of the host site. A new calcium sulfate-based bioactive bone cement (BioCaS) is developed, having simplicity and effectiveness for bone grafting applications. The response of primary human periodontal ligament (hPDL) cells to this material is investigated through in vitro cell culture model so as to qualify it for the repair of periodontal infrabony defects.

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