Open AccessComparison of immunofluorescence and desmoglein enzyme-linked immunosorbent assay in the diagnosis of pemphigus: A Prospective, Cross-sectional Study in a Tertiary Care Hospital
Author(s) -
Deepthi Ravi,
Smitha Prabhu,
Raghavendra Rao,
C Balachandran,
Indira Bairy
Publication year - 2017
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_595_16
Subject(s) - medicine , pemphigus , tertiary care , dermatology , desmoglein 1 , cross sectional study , immunofluorescence , pathology , autoantibody , immunology , antibody
Pemphigus is an acquired immunobullous disorder in which antibodies are directed against epidermal cadherins. Despite the commercial availability and less cost of enzyme-linked immunosorbent assays (ELISAs) to detect antidesmoglein 1 (Dsg1) and anti-Dsg3, immunofluorescence is still widely used for confirmation of diagnosis.