Open AccessAblation of DJ-1 enhances oxidative stress by disturbing the function of mitochondria in epidermal melanocytes
Author(s) -
Man Li,
Fang Wang,
Juan Du,
Limin Wang,
Jianzhong Zhang,
Xifeng Ding
Publication year - 2020
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_593_18
Subject(s) - oxidative stress , reactive oxygen species , mitochondrion , microbiology and biotechnology , mitochondrial ros , oxidative phosphorylation , western blot , apoptosis , gene knockdown , small interfering rna , adenosine triphosphate , transfection , biology , chemistry , cell culture , biochemistry , genetics , gene
Oxidative stress is implicated in the pathogenesis of vitiligo. The function of DJ-1 in oxidative damage of melanocytes is still elusive.