Open AccessThe measurement of serum tumor necrosis factor-alpha levels in patients with lichen planus
Author(s) -
Yeşim Akpınar Kara
Publication year - 2018
Publication title -
indian journal of dermatology/indian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.395
H-Index - 36
eISSN - 1998-3611
pISSN - 0019-5154
DOI - 10.4103/ijd.ijd_474_17
Subject(s) - medicine , pathogenesis , etiology , mucocutaneous zone , proinflammatory cytokine , tumor necrosis factor alpha , cytokine , oral lichen planus , immunology , necrosis , gastroenterology , disease , pathology , inflammation
Lichen planus is a common mucocutaneous inflammatory skin disease with a multifactorial etiology. Cytokines have a key role in its pathogenesis. In our study, we aimed to investigate the relationship between the disease severity and levels of the tumor necrosis factor alpha (TNF-α) cytokine which was considered as a primary cytokine that initiates the cytotoxicity.